Stopping the spread of Peste des Petits Ruminants (PPR) starts with vaccine access in Africa

Written by Stephen Wilson, Director, Research & Development (VITAL projects) and Camilla Benfield, Product Development Lead, Research & Development, GALVmed. Originally published by Farming First.

Imagine that over the course of 10 days, 80 per cent of your livelihood is destroyed. This is a reality for millions of small-scale producers in Africa who depend on sheep and goats for income, nutrition and survival, but have to contend with Peste des Petits Ruminants (PPR), a highly contagious disease with a mortality rate of up to 90 per cent.

Despite being the target of a global eradication campaign, PPR continues to threaten sustainable development, food security and poverty reduction efforts with its rapid spread across borders. Recent outbreaks in Europe demonstrate that no country is free from the risk of PPR.

In our interconnected world, nowhere is safe until everywhere is safe. Eradicating PPR could deliver billions in economic gains, alongside improved nutrition, health and education outcomes. But achieving its global eradication hinges on one key factor: ensuring more vaccines reach the owners of small ruminant livestock who need them.

PPR threatens rural livelihoods, but solutions exist

PPR impacts more than 300 million farming households each year, particularly in low-income countries where small ruminants are the backbone of rural livelihoods. Women and young people, who often manage these animals, suffer the most when outbreaks occur. The loss of sheep and goats not only strips families of a vital food source but also affects household income, children’s education and community resilience.

The disease is endemic in large parts of Africa, the Middle East and Asia, but Southern Africa remains at a tipping point. Six countries in the region, Botswana, Eswatini, Lesotho, Madagascar, Mauritius and South Africa, and one zone of Namibia are still officially PPR-free, yet the disease is spreading southwards and now poses a real threat to uninfected areas.

Without urgent and coordinated action, the disease risks spreading further, potentially reversing decades of progress in poverty alleviation, starting with the regions where small ruminants play a key role in food systems.

What makes the increasing spread of PPR frustrating is that high-quality vaccines that could prevent the disease exist. These vaccines offer lifelong immunity against all PPR strains and are considered one of the most reliable tools available for eradication. Yet vaccination coverage remains dangerously low across much of Africa.

In Uganda, for example, at least half of the districts are currently at risk of PPR outbreaks, putting the country’s 18 million small ruminants, most of which remain unvaccinated, in danger. Low disease awareness, high vaccine costs, inadequate veterinary infrastructure and limited animal identification systems continue to hinder large-scale livestock vaccination. Overcoming these barriers requires not just better vaccine availability but also stronger delivery systems that can reach the most remote farmers.

Why accelerating access to vaccines is crucial

Multiple European countries are now contending with PPR, thought to have spread from Africa. This is a stark reminder that global health security starts with controlling diseases at their source.

Healthy animals in Africa safeguard livelihoods locally while also protecting food security and international trade. To keep small ruminants healthy in the region, vaccine access must improve rapidly, supported by sustained investment and coordinated action.

A key step every African country must take is ensuring that affordable and accessible vaccines reach small-scale producers. GALVmed’s VITAL programme is helping to bridge this gap by supporting the development and distribution of combination vaccines, such as those targeting PPR, contagious caprine pleuropneumonia (CCPP) and sheep and goat pox (SGP).

These farmer-friendly vaccines are designed to be more cost-effective, requiring a single administration to protect against multiple diseases. Morocco’s success in using them to control outbreaks of both PPR and sheep pox demonstrates how such innovations can make vaccination campaigns more efficient while reducing long-term costs.

Regulatory systems also need to move faster. Despite the availability of effective vaccines against PPR, delays in licensing and registration across African markets slow down access. GALVmed and its partners have secured several product approvals, but greater regulatory harmonisation is essential to ensure new vaccines can reach farmers without unnecessary delays.

Finally, expanding vaccination coverage requires bridging the “last mile” to reach remote farming communities. Public-private partnerships have proven highly effective here. Boehringer Ingelheim’s LastMile initiative, for example, has trained animal health technicians, increased veterinary medicine registrations by 86 per cent and reached tens of thousands of small-scale producers across six African countries.

In Mali, trials of LYOPOX-PPR , a combined vaccine against PPR and SGP have vaccinated over 95,000 small ruminants, empowering farmers to proactively manage livestock health rather than respond reactively after outbreaks. Now, a vaccine that protects small ruminants against PPR, SGP and CCPP in a single shot is available in the market in East Africa. By combining innovation, regulatory reform and effective delivery systems, Africa can accelerate vaccine access and build stronger, more resilient animal health systems capable of tackling PPR at its roots.

Investing today protects everyone tomorrow

History shows that stopping devastating livestock diseases is possible. Rinderpest, a similarly contagious cattle disease, was declared eradicated in 2011 after a coordinated global campaign aimed at stopping its spread.

PPR could be next. We have the tools we need to consign it to history. GALVmed’s development of new combination vaccines and successful country-led vaccination campaigns, from Morocco to Mali, show that investment and political will exist to achieve PPR eradication.

Now, investment should be scaled to take these solutions from pilot to widespread coverage, which would be both an act of solidarity and a shield for the rest of the world. If we act decisively, we can protect livelihoods in Africa, prevent the disease from spreading further in Africa and across Europe, and unlock lasting economic and social benefits for millions of families.

The cost of livestock diseases and how vaccination makes a difference

Millions of people in Africa depend on livestock — including cows, sheep, goats, and chickens — for food security and household income. Therefore, when these animals fall ill, livelihoods are directly threatened.

Each year, 20% of livestock production is lost to disease. Fortunately, the solution is within reach: improving the availability and accessibility of high-quality vaccines and medicines to safeguard animal health and, in turn, protect entire communities.

Vaccination is a vital tool in controlling disease outbreaks and preventing devastating losses. Diseases such as Foot and Mouth Disease (FMD), Peste des Petits Ruminants (PPR), Rift Valley Fever (RVF), or Contagious Caprine Pleuropneumonia (CCPP) not only threaten animal health but also endanger nutrition, food security, and household income.

For example, PPR causes economic losses estimated USD 1.2 to 1.7 billion annually, with one-third of the impact in Africa and a quarter in South Asia. CCPP alone has a yearly economic impact of around USD 507 million. Imagine a single vaccine capable of tackling these devastating diseases simultaneously.

Multivalent vaccines — which protect against multiple diseases in a single dose — offer a strong return on investment. They are a cost-effective solution for small-scale producers, reducing the need for multiple interventions and saving time and resources while offering broader protection.

Together with partners, GALVmed has supported the development of multivalent vaccines targeting livestock diseases that most severely impact food security and livelihoods across Africa.

After years of research and development, three of GALVmed’s commercial partners — JOVAC, Hester Biosciences, and M.C.I. Santé Animale — have achieved market authorisation for three multivalent vaccines:

  1. CBPP, Lumpy Skin Disease, and Rift Valley Fever
  2. Newcastle Disease and Infectious Bursal Disease
  3. CCPP, Sheep and Goat Pox, and PPR

With a single shot or administration, farmers can now affordably and effectively protect their herds against multiple diseases, making a meaningful contribution to household nutrition, income, and long-term resilience. This is a powerful return on investment that highlights the inherent value of vaccination.

GALVmed remains committed to supporting the development and commercialisation of livestock vaccines, ensuring that small-scale producers across Africa have access to the tools they need to protect their animals.

By safeguarding livestock health, we help unlock economic stability, opportunity, and sustainable growth. Because when livestock are healthy, farmers thrive and entire communities move forward.

Photo credit: FAO/Luis Tato

Written by Patricia Valdeón Noya as part of the campaign “The Impact of Livestock Diseases”

Vaccinated day-old chicks brings transformational change for Africa’s farmers

This blog was written by Dr Tom Osebe, (Senior Manager, Commercial Development & Impact, Africa, GALVmed) and Dr Marie Ducrotoy (Senior Manager Development Projects and Partnerships, Ceva Santé Animale). Originally published by Farming First.

The power of poultry to boost development in Africa is well known. Cheap to buy and quick to rear, chickens offer small-scale livestock producers across the continent – especially women – an opportunity to increase incomes and improve diets for themselves and their families. It is no surprise that an estimated 1 billion of the world’s poorest people depend on poultry for their livelihoods.

However, poultry diseases remain a persistent threat to small-scale chicken production in Africa. In contrast to other parts of the world where poultry production is integrated and dominated by large players who both produce and rear their chicks, Africa’s fragmented value chain presents unique challenges. African poultry farmers are served by small- and medium-sized hatcheries and many of these have not invested in vaccine technology. 

Compounding the issue is a lack of farmer awareness regarding the existence and benefits of vaccinated day-old chicks. This lack of demand perpetuates a cycle where smaller hatcheries have no commercial incentive to invest in vaccination technology. As a result, the burden of vaccination falls on the farmers themselves. 

Farm vaccination, however, is fraught with challenges. It is technical and requires adherence to a cold chain to ensure vaccine efficacy. Even under optimal conditions, on-farm vaccination typically results in 80 per cent of the flock being vaccinated.

De-risking hatchery vaccination

It seemed like an intractable chicken-and-egg problem: to increase the production of vaccinated day-old chicks in Africa, we need increased demand for them from farmers. But increasing demand requires farmers to buy vaccinated chicks through a better understanding of the value.

Fortunately, we have been able to work on a project that has succeeded in breaking the impasse – one that holds promise for poultry production across the continent. In 2021, Ceva Animal Health teamed with GALVmed, with the support of the Gates Foundation, to implement a game-changing four-year project, PREVENT (Promoting and Enabling Vaccination Efficiently, Now and Tomorrow).

PREVENT used a two-pronged approach to enable medium-sized hatcheries in 11 sub-Saharan African countries to produce high-quality, vaccinated day-old chicks. The funding financed the supply of the necessary vaccination equipment and improved the vaccination facilities, making it financially more accessible for hatcheries to then purchase vaccines. This then enabled Ceva to supply its vaccines to these hatcheries – opening up a major new sector of Africa’s poultry industry.

Crucially, to increase demand for vaccinated chicks, PREVENT also raised awareness of their value among small-scale producers. The project trained 225 field technicians, and of these, 70 field technicians conducted over 20,000 farm visits and held almost 2,000 farmer meetings attended by more than 23,000 women and 20,000 men. As well as highlighting the benefits of purchasing vaccinated day-old chicks, field technicians helped farmers improve their management practices and took samples to better understand circulating diseases and antimicrobial resistance.

Raising farmer expectations

We were delighted – and even a little surprised – to see how effective this approach proved. The sudden increase in farmer demand for vaccinated chicks encouraged a rapid shift in small- to medium-sized hatcheries. Between 2021 and 2025, 37 hatcheries in 11 countries produced 202 million day-old chicks thanks to the project. Of these, 90 per cent – 182 million chicks – were vaccinated, with a total of 494 million vaccine doses administered. This has created a net economic benefit of $43 million over the course of the project.

But these numbers, as impressive as they are, do not tell the full story. By increasing the availability and accessibility of fully vaccinated day-old chicks, and by raising smallholder awareness of their value, PREVENT has achieved a fundamental and permanent shift in farmer understanding and expectations in the countries where it operated. Small-scale poultry producers are no longer willing to settle for unvaccinated chicks.

This new attitude has laid the foundations for a prosperous, self-sustaining and increasingly competitive vaccine market that reaches small-scale producers and reduces vaccine inequality. With PREVENT now coming to a close, we are happy that this legacy will ensure day-old vaccinated chicks continue to reach poultry farmers without the need for additional donor funding.

“PREVENT is a good example of collaboration between parties where the vision was not only realised, but surpassed,” says Dr Pierre-Marie Borne, Senior Public Affairs at Ceva Santé Animale, who was the pioneer of PREVENT and saw the vision of how hatchery vaccination had the potential to impact poultry businesses and millions of small-scale producers across Africa.   

Boosting smallholder livelihoods

And it is these poultry farmers who are now leveraging PREVENT’s achievements for their own empowerment and commercial success. “The results have been so good – it has added to my profits because I no longer have losses as before,” says Victoria Oladijiri, a poultry farmer from Nigeria who switched to purchasing vaccinated chicks as a result of PREVENT. “I use the profits for provisions at home and for so many other good things.” Other farmers to benefit from PREVENT have reported similar positive changes. 

As PREVENT comes to an end, it is our hope that stories like Victoria’s will become the norm throughout Africa, as a thriving vaccines market breaks down the vaccine inequality that has for too long held back the development potential of poultry. We believe the project’s model of de-risking investment in smaller hatcheries, while increasing farmers’ understanding and expectations, holds promise across the continent – both in poultry and even other animal production sectors.

Social extension: Mentoring field technicians to deliver poultry extension services

Mentoring has the power to positively impact everyone involved, as evidenced by an initiative to mentor field technicians in Tanzania to provide inclusive veterinary extension to small-scale poultry producers.

Field technicians from the PREVENT (PRomoting and Enabling Vaccination Efficiently, Now and Tomorrow) initiative were paired with business women (chicken vendors) who had previously participated in the CGIAR’s Women in Business initiative in a unique mentorship program to enable them deliver more equitable extension services to their customers. PREVENT is an initiative of Ceva Animal Health in collaboration with GALVmed and funded by Gates Foundation.

Since 2021, the PREVENT initiative has been working with small-to-mid-size hatcheries in 11 sub-Saharan African countries to produce high-quality, vaccinated day-old chicks. These vaccinated chicks are mostly sold to small businesses. The hatcheries in the PREVENT initiative work with field technicians – women and men who provide technical input to the poultry producers, helping them with much needed flock management, health and husbandry advice, and raising awareness about the benefits of vaccinated chicks, therefore creating demand.

The PREVENT initiative initiated a mentoring program to build the capacity of the field technicians to deliver gender-responsive extension services and qualitatively document lessons learned. Gender-responsive extension services address inequalities by considering the needs, experiences, and roles of women, men, girls, and boys. Other individual characteristics like age, ethnic group, and education level also influence the way people engage with veterinary extension services, hence the term ‘social extension’.

Twelve Field technicians were paired with five mentors over a period of five months. Researchers from the International Livestock Research Institute (ILRI) led the development of the mentoring program and the Tanzania Livestock Research Institute (TALIRI) provided technical guidance.  Content included discussing gendered roles in chicken value chains, restrictive gender norms that can limit women in poultry businesses, and discussing how identities of farmers and extension officers can influence the interactions. Some examples of inclusive extension include considering the best times of day to visit men and women given their other activities, acknowledging contributions and needs for knowledge by less visible people including household employees and children, and considering how the identity of the extension provider will influence their relationship with clients.

The outcome of the mentoring program was positive with the mentees acknowledging that while academic and vocational training focused on veterinary and bioscience content, the social extension aspect was missing and the mentoring program has increased their understanding of gender norms while providing extension services.

I have realized that building up social relationships allows farm owners and managers to freely share insights with field technicians during extension services provision, regardless of skill level or gender.

– Elisha, mentee from Dar es Salaam.

Recognizing women’s ability and their contributions is crucial and providing equal opportunities to both men and women is essential for the development of the poultry value chain. Some large-scale poultry farmers still don’t seem comfortable with women field technicians but let us work hard to deliver quality services that will continue building their trust in us.

– Grace, mentee from Pwani Region.

Agricultural extension and veterinary care in Tanzania’s poultry business are frequently dominated by men. Two of the ten field technicians in the PREVENT project are women. Through the mentorship initiative, field technicians were connected with five young women who were already empowered in the poultry industry. In doing so, the prejudice that social extension is dominated by men was broken. At the level of farmers, field technicians are now providing training on the importance of inclusivity and cooperation on chick rearing activities in households that they visit.

– Laura, Field Technician Coordinator

A seed planted

Even though the mentorship program has concluded, the researchers are optimistic that a seed has been planted into the minds of the young mentees who will go forward to provide inclusive extension services to poultry producers and beyond. The researchers are urging any training programs for veterinary extension workers to incorporate social and gender considerations into their curriculum. Because being inclusive makes good business sense.

Written by Beatrice Ouma (GALVmed), Zoe Campbell (ILRI) & Humphrey Jumba (ILRI)

Empowering Women Livestock farmers through technology

Gender gaps in men and women’s access to resources, inputs and services mean their work in agricultural value chains falls far short of their potential in terms of scale, productivity, and output, causing huge costs to their households. We sit down with Dr Tom Osebe, GALVmed’s Senior Manager for Commercial Development in Africa to discuss how digital tools can empower women livestock farmers and enable them to be active decision makers in the management of livestock production in their homes and communities.   

What are some of the challenges facing women when it comes to adopting new technology in animal health?

Typically in Africa, the animals kept in the household are owned by the husband or significant male, leaving women and their children responsible for offering husbandry services. Adopting technology here suggests exercising management decisions which in many cases does not rest with them. There is also an aspect of penetration of internet services and cost where it is available. Where women don’t handle the income, financing this may be a limiting factor.

What can be done to empower more women to adopt technology in the animal health sector?

Advocacy and education can play a huge role to influence management mandates on the farm to be progressively delegated from men to women. Educating women in farm management practices and entrepreneurship could contribute to more women having a strong influence in growing their mandate in livestock production in their homes. There is also need to institute women friendly financial solutions that are relevant for livestock production to grow their investment capacity.

In your opinion, what would be the results of more women adopting technology in the sector?  

Women tend to juggle many balls in the home beyond livestock keeping. They have to ensure meals are made, water fetched, tend to the children, visit the market and so on. Technology would be a big help in allowing them to stay on top the livestock production aspects when away from home or while undertaking other tasks. Adopting technology will also allow them to manage the farm remotely when they are not able to, due to situations like childbearing or illness. And finally, technology will make work efficient and effective which will directly lead to an increase in productivity of the livestock impacting the wider wellbeing of the family.

What are some of the market technologies GALVmed is working on that might benefit women livestock keepers and how?

GALVmed and some of our partners are working on a number of technologies that will add value to the livestock heath sector. One of them is the Telehealth platform which allows for livestock keepers including women to source for animal health service providers, enjoy remote care of their animals, maintain medical records among other features. On this, we are working with our partner VetNOW – a Digital Health Technology Company focused on driving the global transformation of veterinary healthcare – in consortium with The National Animal Disease Information Service (NADIS) and Africa veterinary technicians’ association (AVTA).

The other platform is the Market Intelligence Platform (MIP). GALVmed has partnered with AgNexus Africa -a Kenya based market research company- on a pilot basis, to develop an integrated MIP with current market size reports and market simulation components for Kenya, Uganda and Tanzania- which is envisaged to support animal health companies to increase their investment in Africa. The MIP is being implemented alongside the agrodealers digitization and professionalization initiative to automate the collection of retailer-based market data and offer training to agrodealer through bespoke International Finance Corporation agrodealer training material. Better managed agrodealer stores will ensure women access a diverse portfolio of high quality products, for use at the farm.

We are striving to be inclusive in these digital platforms so that women can also benefit.

Anything else you’d like to add?

In many cases, there is a good understanding of value in the household. If women are helped to thrive in their livestock keeping, it strongly contributes to empowering them in the home. They progressively will exercise management responsibilities which will contribute to growing the general welfare of the home and the community.

This blog has been written by Beatrice Ouma as part of the International Women’s Day 2025

Digital inclusion: Increasing access to animal health digital technologies by women

In low- and middle-income countries (LMICs), the digitisation of agricultural value chains is enabling access to markets, assets and services for small-scale producers. Digital solutions such as online platforms providing access to farm inputs create efficiencies for both agribusinesses and farmers in the last mile. For example, in animal health, digital procurement solutions can also be bundled with digital advisory services that provide farmers with vital information on livestock disease management.

Women make up at least 43 per cent of the agricultural labour force in developing countries, but they are restricted by social norms and lack of access to resources which may enable them to benefit from digital services. Even though there has been an increase of mobile phone and internet adoption by women, the mobile gender gap is still relatively low at 8%. Women farmers working in agricultural value chains still lack the basic means to access digital services than men, reducing their likelihood of accessing and using digital agriculture solutions. And yet, most of these value chains are increasingly going digital, hindering even more women’s opportunities of progression. So how do we address this challenge and make the technologies more  inclusive?

Key to getting more women to adopt digital technologies is digital literacy training. Digital technology providers and projects need to increase both skills and functionality of these technologies for women farmers so they can use them efficiently, safely, and to their full potential.   

Projects also need to assess which services can best accommodate women farmers and women-led agribusinesses – and it is essential to work with women when rolling out these technologies. For example, information on small animal disease management and poultry could be one area that women are more likely to be interested in and benefit from.

Improving the user experience for female farmers, whether that’s by providing content in a variety of languages or creating a ticket system where female farmers can report difficulty using the services, will also significantly improve adoption by women.

Additionally, including other family members in digital literacy training and adoption, and providing engagement opportunities for male farmers to understand the value of women’s inclusion in digital agriculture services is also important.

GALVmed and partners are working on some crucial animal health digital platforms including a Market Intelligence Platform which is an online platform to address the lack of market data in Africa, and a tele-medicine/digital services app specifically catering for African small scale livestock producers. The telemedicine app will enable remote livestock care, and another complementing app for clinical sign recognition uses images of livestock diseases and symptoms to increase the accuracy of diagnosis.

As we move closer to rolling out these platforms and apps for use by small-scale producers, it is important to be gender aware of how they can be targeted to include female livestock producers, so no one is left behind. As the world works towards building more sustainable and resilient food systems, it is essential to include and empower women farmers to play their critical role in feeding the world. Digital technologies can empower women and promote gender equality in the agricultural sector and inclusion is very crucial now more than ever.

This blog has been written by Beatrice Ouma as part of the International Women’s Day 2025

Photo credit: Agnexus/Envato

Celebrating Success: A Look at GALVmed Achievements

For small-scale livestock producers in the global south, a goat, cow, or flock of chickens are not just animals – they are the foundation of their livelihoods. Livestock provide food, income, and security, and losing them to preventable diseases can be devastating.

In a world where over a billion people depend on livestock, improving animal health is critical not only to protect individuals but also to ensure sustainable agricultural systems, food security and safety, and entire community’s well-being and progression.

GALVmed continues to collaborate with partners and key public and private stakeholders to transform the lives of small-scale producers across Africa and South Asia through improved animal health. Our approach remains the same: enhancing the availability, accessibility, awareness and adoption of high-quality veterinary medicines to reduce productivity and animal losses from preventable diseases. And how does this translate into tangible actions?

  • Improving availability: By researching, improving and developing much needed animal health products and solutions suited to the needs of small-scale livestock producers.
  • Increasing accessibility:  By easing barriers in the regulatory and policy environment ensuring the needed products reach the markets and are accessible and affordable to small-scale livestock producers.
  • Increasing awareness and adoption: By using appropriate channels to reach the last mile providing information and veterinary medicines to small-scale livestock producers.  
  • Increasing understanding: By providing practical data and information from the small-scale livestock producer field to measure impact and facilitate data-driven decisions.

Over the years, GALVmed through its partners, has implemented impactful programmes across Africa and South Asia, leading to significant achievements:

  • 2.9 billion livestock vaccines, therapeutics and other animal health products sold to small-scale customers across Africa and South Asia, of which 1.3 billion doses were vaccines and the remainder therapeutics, parasite treatments and supplements (2014-2023).
  • 6.2 million estimated cumulative annual customers served (2014-2023).
  • 38.7 million livestock deaths averted saving the sector approximately of $359 million (2014-2023).
  • Approximately $126 million in poultry deaths averted from Newcastle disease, excluding benefits derived from the project PREVENT (2014-2023).
  • 16 animal health products taken to full development since 2010.
  • A total of 19 products registered under the Mutual Recognition Procedure (MRP) to date.
  • Over 100 publications disseminated.

GALVmed will continue to work closely with partners to make effective animal health products accessible across sub-Saharan Africa and South Asia, advancing our mission to safeguard livestock health to consequently improve human lives.

How to bridge the divide across Africa’s fragmented veterinary medicine sector

This blog was written by GALVmed CEO, Carolin Schumacher and published by CNBC-Africa.

From backyard chicken raising to the grazing cattle of nomadic pastoralists, across much of rural Africa, animal diseases travel faster and wider than veterinary medicine.

An estimated 800 million people keep chickens, goats and cattle across the continent as valuable sources of food, income, fuel and fibre. Yet across Africa, the most prominent livestock diseases cost an estimated $9 billion every year – roughly 6% of the total value of the continent’s livestock sector.

Protecting and treating animals across such a vast and disparate population and geographic expanse is complicated and costly. Getting vaccines and medicine to livestock in remote areas of Africa is often limited by a lack of knowledge, manpower, funding and reliable refrigerated transport. Even when resources exist, they are typically spread too thin to systematically protect animal health and, by extension, the incomes of livestock keepers.

With a rapidly growing population and demand for animal-derived protein, enabling the veterinary sector to address the diverse needs and challenges of small-scale producers is not only possible, but also critical to Africa’s sustainable development.

Entrusted with the safeguarding of national herds, government veterinary services have historically focused on the most detrimental diseases affecting large-scale livestock operations, leaving many small-scale farmers behind.

Efforts in the past have successfully dealt with damaging infectious livestock diseases, including eradicating the deadly cattle disease rinderpest in 2011 through an integrated global campaign. Yet existing government-led efforts to manage other contagious livestock diseases are now lagging.

Facing rising economic pressures and a significantly broadened mandate, many African governments can no longer achieve sufficient vaccination coverage and deliver “last mile” services that saw volunteers across the continent contribute to rinderpest’s eradication even in the most remote communities.

Comprehensive livestock health management today requires governments and other livestock health organisations to think holistically and consider the infectious diseases limiting small-scale livestock producers’ potential. This includes foot and mouth disease, lumpy skin disease and contagious bovine pleuropneumonia (CBPP) in cattle, as well as peste des petits ruminants (PPR), sheep and goat pox and contagious caprine pleuropneumonia (CCPP) in sheep and goats.

Meanwhile, the global veterinary medicine industry has traditionally focused on addressing livestock health issues of the Global North, where the profitable markets justify the high cost of investments in research and development of new products.

Small-scale producers of large and small ruminants – cattle, sheep, and other grazing animals – in the Global South have not benefitted from such investment. A commercially viable market for ruminant vaccination does not currently exist. Where it does, it can be regularly undermined by free mass vaccination by governments, non-governmental organisations and development agencies. Simply put, there are not enough private veterinary vaccination efforts supporting small-scale livestock producers.

In recent years, the Global Alliance for Livestock Veterinary Medicines (GALVmed) and several private animal health companies have succeeded in developing and bringing to market a more complete portfolio of affordable animal vaccines and medicines for small-scale livestock producers in the Global South. Further, combined efforts in the poultry sector have demonstrated that governments and businesses sharing responsibility can foster a functioning veterinary service sector and vibrant, locally adapted veterinary medicine infrastructure and industry that caters to the specific needs of small-scale producers.

In practice, this means creating demand through increased awareness about livestock diseases while providing uninterrupted access to affordable veterinary products at the farm level. Adequately addressing the needs of the continent’s tens of millions of small-scale producers requires opening the ruminant vaccines market for private sector development, particularly for vaccine suppliers, local supply chain actors and private veterinary service providers.

Improving product registration and distribution will also help to equip farmers across Africa with the tools needed to preserve their animals’ health and support food security and economic growth on the continent, including their own.

Together with our partners, GALVmed has delivered more than 1.2 billion vaccines and other animal health products to farmers across Africa and South Asia, preventing the deaths of more than 23 million livestock – and the associated impacts this has on farmers’ incomes and food security.

Currently, GALVmed’s partners are developing a suite of combination vaccinations that address multiple infectious livestock diseases with a single intervention. These new vaccines promise to facilitate and improve vaccination access for farmers. Preventing multiple diseases at a lower cost will protect their livestock and livelihoods more completely and for the long term.

The vision of a food-secure, resilient African continent is well worth the efforts of removing the barriers to the functioning of the African small-scale livestock-producing sector. When governments, policymakers, veterinarians and veterinary medicine developers put the needs of small-scale producers first, they can help fill the gaps of the fragmented livestock health sector. Today, most tools are available but stakeholders will have to work together to deliver them to the farmers who need them most, for the benefit of Africa’s small-scale livestock-producing sector and society at large.

Photo credit: GALVmed/Buta Photography. A woman selling veterinary medicines in Ghana, 2022.

How Clinical Diagnostics Could Help the Global Fight Against Antimicrobial Resistance

This blog was written by Thembinkosi Ramuthivheli (GALVmed), Marie-Elodie Le Guen (Ceva), and Dr. Pierre-Marie Borne (Ceva). Originally published by Farming First.

The misuse of antibiotics in both human and animal health has created an urgent health emergency globally. The resistance of microbes to antibiotics that are constantly used to combat them makes infections harder to treat, creating an antimicrobial resistance (AMR) crisis directly responsible for up to 1.27 million global human deaths as of 2019.

In developing countries, the challenges created by AMR are even more pronounced. Many small-scale producers, desperate to treat their infected livestock, turn to and misuse the most readily available antibiotics, further exacerbating the resistance to antibiotics while increasing losses due to death. As a result of the increasing threat of this phenomenon, AMR has become one of the priorities of the quadripartite agreement and the 2024 UN High-Level Meeting aimed at ramping up global action.

Essential diagnostic tools have also been initiated in several cities to aid in selecting the right antibiotics for specific livestock infections. Diagnostics have the potential to aid veterinarians in assisting farmers to identify specific disease-causing bacteria, allowing for the rationalised use of antibiotics. However, these tools are not easily accessible to small-scale producers in rural areas, setting the world several steps backwards in efforts to effectively combat the growing threat of AMR​.

Combating antimicrobial resistance with the OneLab Initiative

Small-scale producers generate about one-third of the world’s food supply and bear a significant brunt of the risks of AMR. To address the access gap between them and essential diagnostic tools to tackle microbial infections, Ceva Laprovet’s OneLab Initiative, in partnership with GALVmed, is supporting with a solution that brings clinical diagnostic services closer to small and medium-sized commercial farms. Traditionally, small-scale producers in poultry areas have faced difficulties accessing diagnostic tools, as laboratories that have them are often located far away and primarily in big cities. The long distances, challenges of transportation and delays in results have prevented farmers from getting the timely help they need when their poultry or livestock fall ill​.

OneLab technicians performing tests in one of the diagnostic centers, Senegal, 2023. . Credit: GALVmed/Mediaprod

The OneLab Initiative seeks to bridge this gap by setting up small laboratory units with diagnostic tools at veterinary clinics in poultry areas. Accessing diagnostics in these clinics allows for quick detection of bacterial infections which helps veterinarians recommend the most appropriate treatment for infected flocks, ensuring farmers use the right antibiotic while reducing the risk of antimicrobial resistance in their livestock.

The first tool introduced under the initiative is the orientation antibiogram, a practical diagnostic test that provides results in less than 24 hours. This enables veterinarians to determine not only if antibiotics should be used, but also which specific antibiotic will be most effective. This rapid feedback is critical in reducing the time farmers would otherwise spend on trial-and-error treatments, minimising losses due to disease​ and also ensuring overall reduction of the use of antibiotics.

Getting results in Senegal

In Senegal, the OneLab initiative has successfully calculated the level of resistance to antibiotics from different bacteria in the poultry sector. In 2023, the initiative was responsible for conducting up to 530 tests representing a total flock of 6.5 million birds across commercial poultry farms​. The data collected from these tests has provided valuable insights into the general level of resistance to antibiotics in the region as well as clinical information and evidence to accurately track their occurrence.

For instance, more than half of the bacteria tested were found to be resistant to most of the antibiotics commonly used by farmers in the region​. Without the diagnostics, veterinarians were blind to the sensitivity of different bacteria to specific antibiotics, often leading to the prescription of antibiotics that do not work. Farmers were also unaware of drug-resistant infections and effective measures to combat them before they led to unnecessary deaths among their flocks.

Poultry farmer feeding his flock in Senegal, 2023. Credit: GALVmed/Mediaprod

With diagnostic tools at their disposal, farmers who previously had to rely on a trial-and-error approach could now make informed decisions with the guidance of local veterinarians to reduce the losses of their livestock. This also helps them save significant sums of money by avoiding the purchase of ineffective antibiotics.

Moreover, the OneLab Initiative has sparked broader discussions about AMR within the veterinary community in Senegal. Annual meetings with veterinary authorities have raised awareness of drug-resistant microbes and the importance of diagnostics in combating their threat to animal lives. This growing awareness is essential to changing the mindset of both veterinarians and farmers when it comes to the advantages of the rational use of antibiotics​.

Clinical diagnostics as a path forward

Introducing diagnostics to veterinary clinics in poultry areas ultimately changes the paradigm of livestock management for both veterinarians and Small-scale producers. Livestock farmers in rural areas could have access to better antibiotic treatment options whenever a microbial infection is detected. This reduces the need for cycling through different antibiotics, as diagnostics offer a precise understanding of the infection.

Reducing poultry producers’ reliance on antibiotics helps to curb the further spread of drug-resistant microbes​. This change in approach, supported by diagnostics, also provides veterinarians with the ability to offer more accurate diagnostic services, improving the overall treatment of livestock. Farmers, in turn, are encouraged to adopt healthier practices that improve the health of their livestock while reducing the risk of antimicrobial resistance in them – a perfect win-win situation​.

The OneLab Initiative has demonstrated that more precise diagnostics can play a vital role in helping farmers rationalise their use of antibiotics to reduce the risks of antimicrobial resistance in their livestock. In Senegal, the number of diagnostics to get accurate solutions to bacterial infections in poultry has steadily increased since the initiative was launched. With this success, it is evident that introducing diagnostics in local veterinary clinics offers a scalable model that can be implemented in other regions suffering from similar challenges​. Initiatives bridging farmers’ access to diagnostics tools ultimately need worldwide support and visibility in order to increase their adoption as a viable solution to combat the growing antimicrobial resistance threat.

Header photo credit: ©2023 GALVmed/Mediaprod

Modelling and field studies: Essential M&E tools to understand our impact

Healthy livestock are the cornerstone of many communities’ economies and well-being, making access to high-quality, safe, and effective animal health solutions critical to secure small-scale producers livelihoods and avoid substantial economic losses in Africa and South Asia.

At GALVmed, we partner with commercial, governmental, and non-governmental actors to increase the availability and accessibility of vaccines and essential animal health products to small-scale livestock producers (SSPs) in Africa and South Asia. However, it is equally important to ensure that these products are purchased and used by farmers to prevent or treat livestock and poultry diseases. Adoption of animal health medicines goes beyond a simple purchase; it triggers a cycle that improves animal health, boosts productivity, and enhances the wealth and well-being of these producers and their communities.

Understanding how adoption translates into economic and other benefits for SSPs is central to our mission. Monitoring and Evaluation (M&E) gives us a structured way to assess these outcomes. It is not just a check box or data collection exercise; it is about understanding the difference we are making in SSPs’ lives.

Given the vast scope and scale of our work across multiple countries and contexts, modelling is one of our key tools for understanding adoption and impact. Modelling refers to the use of mathematical and statistical methods, using epidemiological and economic data, to simulate and evaluate the potential effects and outputs of a programme or intervention. This is a powerful tool that helps organisations make informed decisions. Modelling allows us to process veterinary product sales data and estimate the resultant economic benefits for SSPs. This helps us to see and quantify how our interventions are impacting small-scale producers.

For example, in 2023 we partnered with Supporting Evidence based Interventions-Livestock (SEBI-L) to apply the model to GALVmed PLSHL 2 initiatives between 2014 and 2017. The model estimated a total NEB of $105.1M in economic benefits to the 3,664,114 estimated customers reached.

To complement our modelling work, we also conduct field studies to gain deeper insights into the changes in SSPs’ lives. These field studies allow us to gain contextual understanding to better understand the context within which our initiatives are embedded. They also allow us to dive deeper into the changes occurring in the lives and livelihoods of SSPs. By combining modelling with on-the-ground research, we get a more holistic understanding of our impact, ensuring that we can learn from  both our successes and areas where we can improve.

Ensuring the availability and the adoption of veterinary products is central to sustainable and resilient agricultural practices. From a systems perspective, GALVmed ‘s transformational market systems change framework will help us to understand the systems changes driven by our partnerships and efforts to improve access to and adoption of veterinary medicines. This framework will help us see where and how our work is contributing to long-term, systemic change, ensuring that we make a lasting impact on those who need it most.

This blog was written by Katharine Tjasink, Senior Manager, Impact, Evaluation & Learning, as part of the campaign ”M&E: Designing for Impact”.