Tag: vaccination

How Clinical Diagnostics Could Help the Global Fight Against Antimicrobial Resistance

Posted on by team galvmed

This blog was written by Thembinkosi Ramuthivheli (GALVmed), Marie-Elodie Le Guen (Ceva), and Dr. Pierre-Marie Borne (Ceva). Originally published by Farming First.

The misuse of antibiotics in both human and animal health has created an urgent health emergency globally. The resistance of microbes to antibiotics that are constantly used to combat them makes infections harder to treat, creating an antimicrobial resistance (AMR) crisis directly responsible for up to 1.27 million global human deaths as of 2019.

In developing countries, the challenges created by AMR are even more pronounced. Many small-scale producers, desperate to treat their infected livestock, turn to and misuse the most readily available antibiotics, further exacerbating the resistance to antibiotics while increasing losses due to death. As a result of the increasing threat of this phenomenon, AMR has become one of the priorities of the quadripartite agreement and the upcoming 2024 UN High-Level Meeting aimed at ramping up global action.

Essential diagnostic tools have also been initiated in several cities to aid in selecting the right antibiotics for specific livestock infections. Diagnostics have the potential to aid veterinarians in assisting farmers to identify specific disease-causing bacteria, allowing for the rationalised use of antibiotics. However, these tools are not easily accessible to small-scale producers in rural areas, setting the world several steps backwards in efforts to effectively combat the growing threat of AMR​.

Combating antimicrobial resistance with the OneLab Initiative

Small-scale producers generate about one-third of the world’s food supply and bear a significant brunt of the risks of AMR. To address the access gap between them and essential diagnostic tools to tackle microbial infections, Ceva Laprovet’s OneLab Initiative, in partnership with GALVmed, is supporting with a solution that brings clinical diagnostic services closer to small and medium-sized commercial farms. Traditionally, small-scale producers in poultry areas have faced difficulties accessing diagnostic tools, as laboratories that have them are often located far away and primarily in big cities. The long distances, challenges of transportation and delays in results have prevented farmers from getting the timely help they need when their poultry or livestock fall ill​.

OneLab technicians performing tests in one of the diagnostic centers, Senegal, 2023. . Credit: GALVmed/Mediaprod

The OneLab Initiative seeks to bridge this gap by setting up small laboratory units with diagnostic tools at veterinary clinics in poultry areas. Accessing diagnostics in these clinics allows for quick detection of bacterial infections which helps veterinarians recommend the most appropriate treatment for infected flocks, ensuring farmers use the right antibiotic while reducing the risk of antimicrobial resistance in their livestock.

The first tool introduced under the initiative is the orientation antibiogram, a practical diagnostic test that provides results in less than 24 hours. This enables veterinarians to determine not only if antibiotics should be used, but also which specific antibiotic will be most effective. This rapid feedback is critical in reducing the time farmers would otherwise spend on trial-and-error treatments, minimising losses due to disease​ and also ensuring overall reduction of the use of antibiotics.

Getting results in Senegal

In Senegal, the OneLab initiative has successfully calculated the level of resistance to antibiotics from different bacteria in the poultry sector. In 2023, the initiative was responsible for conducting up to 530 tests representing a total flock of 6.5 million birds across commercial poultry farms​. The data collected from these tests has provided valuable insights into the general level of resistance to antibiotics in the region as well as clinical information and evidence to accurately track their occurrence.

For instance, more than half of the bacteria tested were found to be resistant to most of the antibiotics commonly used by farmers in the region​. Without the diagnostics, veterinarians were blind to the sensitivity of different bacteria to specific antibiotics, often leading to the prescription of antibiotics that do not work. Farmers were also unaware of drug-resistant infections and effective measures to combat them before they led to unnecessary deaths among their flocks.

Poultry farmer feeding his flock in Senegal, 2023. Credit: GALVmed/Mediaprod

With diagnostic tools at their disposal, farmers who previously had to rely on a trial-and-error approach could now make informed decisions with the guidance of local veterinarians to reduce the losses of their livestock. This also helps them save significant sums of money by avoiding the purchase of ineffective antibiotics.

Moreover, the OneLab Initiative has sparked broader discussions about AMR within the veterinary community in Senegal. Annual meetings with veterinary authorities have raised awareness of drug-resistant microbes and the importance of diagnostics in combating their threat to animal lives. This growing awareness is essential to changing the mindset of both veterinarians and farmers when it comes to the advantages of the rational use of antibiotics​.

Clinical diagnostics as a path forward

Introducing diagnostics to veterinary clinics in poultry areas ultimately changes the paradigm of livestock management for both veterinarians and Small-scale producers. Livestock farmers in rural areas could have access to better antibiotic treatment options whenever a microbial infection is detected. This reduces the need for cycling through different antibiotics, as diagnostics offer a precise understanding of the infection.

Reducing poultry producers’ reliance on antibiotics helps to curb the further spread of drug-resistant microbes​. This change in approach, supported by diagnostics, also provides veterinarians with the ability to offer more accurate diagnostic services, improving the overall treatment of livestock. Farmers, in turn, are encouraged to adopt healthier practices that improve the health of their livestock while reducing the risk of antimicrobial resistance in them – a perfect win-win situation​.

The OneLab Initiative has demonstrated that more precise diagnostics can play a vital role in helping farmers rationalise their use of antibiotics to reduce the risks of antimicrobial resistance in their livestock. In Senegal, the number of diagnostics to get accurate solutions to bacterial infections in poultry has steadily increased since the initiative was launched. With this success, it is evident that introducing diagnostics in local veterinary clinics offers a scalable model that can be implemented in other regions suffering from similar challenges​. Initiatives bridging farmers’ access to diagnostics tools ultimately need worldwide support and visibility in order to increase their adoption as a viable solution to combat the growing antimicrobial resistance threat.

Header photo credit: ©2023 GALVmed/Mediaprod

PREVENT: How hatchery vaccinations are boosting poultry production in Africa

Posted on by team galvmed

Marie Ducrotoy, Senior Manager Development Projects and Partnerships, Ceva Santé Animale

Tom Osebe, Senior Manager, Commercial Development & Impact, Africa, GALVmed

Improvement in poultry production is one of the most promising options to provide affordable protein and other essential nutrients to Africa’s rapidly growing population, but poultry diseases pose a constant threat to productivity, and limit the industry’s potential. Even though vaccination is proven as an effective way of protecting poultry, high temperatures in Africa make distribution of vaccines (which mostly need to be kept cold) a challenging task in the continent. This hurdle, combined with a lack of information about circulating infectious diseases, exposes small-scale producers to the risk of losing their flocks and livelihoods overnight.

In 2021, Ceva Santé Animale in partnership with GALVmed, and with the support of the Bill & Melinda Gates Foundation (BMGF), launched the PREVENT (PRomoting and Enabling Vaccination Efficiently, Now and Tomorrow) initiative to introduce hatchery vaccinations for day old chicks (DoC) in mid-size hatcheries in Africa. The overarching objective was to enable small-scale poultry producers in Africa to become more productive and efficient and to enhance their prospects for progression and advancement in the industry. And the targets were ambitious; over 50 million hatchery-vaccinated day-old chicks distributed annually through 36 medium-sized hatcheries spread across eight Africa countries. These were expected to benefit 150,000 poultry producers.  

Three years since inception and with over a year left on the project, PREVENT has performed remarkably and is on track to achieving, and in some instances exceeding, its targets. Already, 31 hatcheries in 11 countries have been equipped to provide vaccinations to DoCs benefitting over 100,000 poultry farmers.

More vaccines for improved immunity and reduced mortality

Because chickens are susceptible to a range of infectious diseases that can impact their health and growth, it is important they are vaccinated with several vaccines on the day of hatch. At an average of three doses per vaccinated day-old chick (vDoC), small-scale producers are benefitting from a much larger range of vaccination covering more disease than before, which in turn improve the quantity and quality of the birds. PREVENT has succeeded in vaccinating over 98 million DoCs, exceeding the 56 million originally targeted. This is attributed to the unexpected success of most hatcheries transitioning from zero to one hundred percent vaccination, in contrast to the staged gradual increase in vaccination which had been modelled. Overall, 91% of DoCs produced by the hatcheries are vaccinated.  

Additionally, twenty vaccines have been registered variably in the West African Economic and Monetary Union- UEMOA region (Benin, Burkina Faso, Guinea-Bissau, Ivory Coast, Mali, Niger, Senegal and Togo) as well as Nigeria, Tanzania, Ethiopia, Ghana and Rwanda offering a diverse offering for use by hatcheries.

Technical support to farmers

Implementing vaccination measures alone is not enough, training on animal health practices, market development opportunities, and advice on biosecurity and good management practices is an important part of the solution for small-scale producers. PREVENT is working with over 200 Field Technicians who have been trained and who serve as the crucial link between the hatcheries and producers. They are providing advice and technical support to the poultry producers and helping to build the customer base of the hatcheries.

A boost for poultry disease data

The SAFER (Sub-Saharan Africa Field Epidemiological Research) portion of the PREVENT project was designed to assess the aetiology of disease outbreaks. Through existing network of field technicians, valuable data on circulation of specific poultry viruses has been collected. This data will be use Ceva and GALVmed to assess if the current vaccines and vaccination program are adequate to protect against  circulating viruses. The data will also be useful to policymakers, hatcheries and their customers for effective disease control. Activities in the SAFER project are providing a significant boost for available epidemiological data for Africa.

Understanding gender dynamics in poultry farming

In order to positively impact women chicken producers through the hatchery intervention, the initiative sought to bring a pragmatic level of understanding of gender dynamics within the poultry sector.  A gender landscaping analysis is helping to shed light on these dynamics which can guide how women can benefit from poultry interventions in the future.

PREVENT has brought about lasting transformational market change as more farmers embrace vaccinated DoCs due to the benefits they offer. Ceva is continually working to create awareness of the advantages of vaccinated DoCs through simplified communication to farmers focusing on better protection improved poultry health, less work for the farmer, and better performance and more money for producers.

Why combination vaccines are better for small-scale livestock producers

Posted on by team galvmed

Written by Stephen Wilson, Director, Research & Development (VITAL projects) and Kellen Asena, Senior Marketing Manager, GALVmed. Originally published by Farming First.

Livestock is a crucial source of income for small-scale livestock producers. Globally, it is estimated that around 78 per cent of the world’s poorest communities rely on agricultural work to support their livelihoods and households. However, livestock diseases represent $358.4 billion in lost production per year.

Access to veterinary care is a critical piece of the puzzle, with higher vaccination rates associated with higher productivity. However, expensive vaccines often do not reach those who rely on healthy animals the most for their livelihoods, income and food security: small-scale livestock producers.

Small-scale livestock producers often live in remote areas and face many constraints around access to veterinary care, including the lack of financial means to pay for the necessary medicines, and sometimes even lack of knowledge on some of the diseases that their livestock may suffer from. Often, suitable vaccines are distributed in disproportionate pack sizes or are simply unavailable. However, combination vaccines, also known as multi-valent vaccines can address these access challenges and more, offering the best value for resource-poor livestock keepers.

Alternatives for smallholder farmers

The prevalence of diseases such as Contagious Bovine Pleuropneumonia (CBPP) and Peste des Petits Ruminants (PPR) in livestock is rife across the African continent, causing significant economic losses for farmers and harm to animal health and welfare. Yet, major gaps exist in the portfolio of products required by small-scale producers to effectively control pressing livestock diseases. Combination and concurrent vaccines, meaning those which target more than one disease in a single dose or administration, offer effective and affordable value to small-scale producers with an outstanding return on investment and a multitude of benefits.

For instance, combination vaccines are more cost-effective than single-use vaccinations, which tend to be more expensive. The Sheep Goat Pox/PPR combination vaccine, for example, is 40 per cent cheaper than the cost of the two vaccines delivered separately. 

Multi-valent vaccines also provide maximum coverage against multiple diseases, rather than simply one livestock disease. They require just a single dose to be administered and therefore are less burdensome on the farmer, the animal, and the veterinarians. There have also been improvements around pack sizes, with 10, 50 and 100 doses available.

Developing multi-valent vaccines

Together with partners, GALVmed is funding the development of several multi-valent vaccines against livestock diseases that are most endemic across Africa and South Asia and currently have the most negative impacts on food security for smallholder farmers. Contagious Caprine Pleuropneumonia (CCPP), for example, can result in economic losses of over $507 million per year in endemic areas, while PPR is highly contagious and affects almost 70 countries across the African continent. SGP affects goats and sheep and can lead to economic losses amounting to $48 million per year across Africa, the Middle East, and Asia. Other diseases that combination vaccines are targeting include Contagious Caprine Pleuropneumonia (CCPP), Lumpy Skin Disease (LSD), Newcastle Disease (ND), and Infectious Bursal Disease (Gumboro) (IBD).

For example, the CCPP/PPR/SGP combination vaccine for small ruminant diseases in affected regions ensures maximum disease coverage using a single vaccine and through distribution networks operating effective cold chains. This combination vaccine is significantly cheaper than monovalent vaccines. The addition of the RVF dosage to the CBPP+LSD/Rift Valley Fever vaccine – known as a concurrent vaccine – is of particular importance to smallholder farmers as it offers enhanced protection against RVF outbreaks when administered at the same time.

Other combination vaccines include the bi-valent PPR/SGP vaccine – of which GALVmed, together with a commercial partner, has sold over 27 million doses to date – as well as multi-valent vaccines against ND and Infectious bronchitis.

Looking ahead

Encouraging governments across the Global South to open up the market for private sector development could ensure small-scale farmers are able to purchase vaccines more easily and efficiently, which is particularly important in the case of a disease outbreak when a rapid response time could make or break disease control efforts.

It is estimated that 800 million people in Africa rely on healthy livestock for their livelihoods. One of the fastest-growing agricultural subsectors in developing countries, livestock accounts for around 30 per cent of agricultural GDP. However, smallholder farmers in low-income, rural areas often lack access to vaccinations and veterinary care resulting from logistical and supply chain difficulties and costs. Combination vaccines could be the answer, offering a viable and cost-effective alternative for small-scale livestock farmers all around the world.

Evaluating the effects of Newcastle Disease vaccination on poultry production and livelihoods

Posted on by team galvmed

Backyard chickens are a significant source of income and nourishment in developing countries, but outbreaks of poultry diseases like Newcastle Disease (ND) severely affect productivity, flock mortality, and consequently, farmer livelihoods.

GALVmed has made important progress in combating ND with the successful development of two thermotolerant vaccines suitable for the rural environment. Vaccination is a cost-effective means to controlling ND. However, to fully grasp the benefits of vaccination interventions and establish evidence-based approaches for developing future programmes and planning, we need to measure vaccination impacts comprehensively. In order to understand and quantify the causal effects of ND vaccination on poultry production and livelihoods, in 2020, GALVmed contracted Oxford Policy Management (OPM) to design and implement, in collaboration with Tufts University, a Newcastle Disease Vaccine (NDV) intervention paired with a rigorous evaluation in rural areas of Tanzania.

The study encompasses two main activities. Firstly, a Newcastle Disease vaccination intervention in selected small-scale farming areas of Tanzania, specifically in the districts of Chemba and Mbozi. To execute this intervention plan, Community Vaccinators are tasked to visit each registered small-scale producer (SSP) household at their doorstep to:

  1. Vaccinate chickens with the I-2 Newcastle Disease vaccine, which is administered by the eye-drop method.
  2. Deliver specific training and knowledge content on the disease, vaccination, and improved poultry-rearing practices.

The second activity involves an experimental study to quantify the causal effects of the Newcastle Disease vaccination intervention. To assess these effects, the impact study was structured as a randomised controlled trial (RCT) where the study sample of intervention villages was randomly divided into two groups for comparison: a treatment group that received the ND vaccination intervention package (vaccination and training), and a control group that did not. The control group will receive one round of the intervention after the study’s endline survey.

Both the vaccination intervention and the impact study are currently underway.  OPM has completed all 6 vaccination rounds in the study’s treatment villages with one pending vaccination round to control villages. The households that were selected for the impact study have been interviewed at the project’s outset, followed by a midline assessment, and will again be interviewed at the end of the intervention. The midline survey revealed preliminary positive outcomes with reduced ND outbreaks and chicken mortality due to NDV delivery.

Underlying this intervention is a key assumption that offering NDV at an affordable price to poultry-keeping households in treatment villages, together with the promotion of improved poultry-rearing practices, will yield noteworthy benefits with respect to poultry productivity, income from poultry, household welfare, food consumption, and possibly decisions on income-generating activities.

The findings derived from this study will allow us to make informed decisions regarding ND vaccination and further enhance the effectiveness of our efforts in protecting poultry health and livelihoods.

Further details and final findings will be made available at the end of the intervention in 2024.

Vaccine Equality is as Vital for Livestock as for People

Posted on by team galvmed

Written by Enrique Hernández Pando, GALVmed’s Executive Director, Commercial Development & Impact.

For 33-year-old mother-of-seven and poultry farmer Helena Kindole in Chanya village in Tanzania, one of the main barriers to growing her chicken business is a lack of access to health services. But not for herself or her family – for her animals.

With smallholder poultry farming often a lifeline for millions of low-income and rural families – accounting for 80% of poultry production in the region – access to medicines and vaccines is just as important for livestock as it is for people. And yet, logistical, infrastructural, and supply challenges are hindering access to veterinary services across the African continent and therefore, holding back smallholder productivity.

At the same time, a rapidly industrialising poultry sector in many developed countries, and an increase in grain prices globally, coupled with cheap imports from more developed markets and low access to animal health care is driving inequality between small- and large-scale producers, threatening to squeeze out smallholder poultry farmers.

Thankfully, this is starting to change. Animal health initiatives are helping local hatcheries to vaccinate chicks against common and damaging diseases before selling them to small-scale farmers, who rear the chicks until they are six months old, eventually selling them to neighbours, restaurants, and other businesses nearby.

For women like Helena, who make up nearly half of the global agricultural workforce in developing countries and in sub-Saharan Africa, the poultry sector offers a crucial source of income and healthy animals are essential for decent livelihoods.

Equipping farmers with the right tools can help to set them up for success to compete alongside more industrialised production systems.

Introducing vaccinations at local hatcheries can strengthen small-scale producers’ sustainability and commercial clout. Supporting these hatcheries with the necessary vaccination equipment and expertise means they can provide customers with large numbers of chicks that are vaccinated against common poultry diseases, such as Newcastle disease and Infectious bronchitis, the former of which contributes to 60% of poultry mortalities in many African countries. This reduces the risk of bird loss, contributing to improved income and more successful businesses overall.

PREVENT project in Tanzania/Iringa, 2021, Helena Kindole. Credit: Colin Dames/CEVA

But implementing vaccination measures alone is not enough, as a lack of technical support and knowledge on zoonoses and other infectious diseases that affect poultry can also hinder productivity. Training on animal health practices, market development opportunities, and advice on biosecurity, good management practices, and more are also crucial pieces of the puzzle. Providing this can help to level the playing field between large scale, industrial hatcheries and small-scale producers.

The PREVENT project (Promoting and Enabling Vaccination Efficiently, Now and Tomorrow) is one example of an initiative working to improve poultry production for Africa’s rapidly growing population. In just two years, this four-year initiative has administered 159 million vaccine doses and vaccinated 49 million hatchery chicks. It has also trained 100 field technicians who have conducted 2,600 farm visits and held over 1,400 farmer meetings across four countries in sub-Saharan Africa, to date.

A low-input but high-producing sector, raising chickens offers a reliable pathway out of poverty for many rural households. A small-scale producer can easily sell their chicks or chickens at the market as they are more affordable for the consumer than beef, for example, but also bring a myriad of other benefits. They add value to social structures, are high in protein, and, on top of this, can directly benefit women who in fact make up the majority of smallholder poultry farmers in the developing world.

Small-scale chicken farmer in Tanzania/Arusha, 2015. Credit: Karel Prinsloo/GALVmed

Against the backdrop of a global cost of living crisis, record-breaking temperatures, and ongoing conflicts, closing the inequality gap for smallholder farmers is critical to build a sustainable future for all. Supporting small-scale producers with training, animal health measures, and much more can help to level the playing field, one small-scale producer at a time, just like Helena.

Celebrating 2 years of achievements with PREVENT

Posted on by team galvmed

Poultry is an affordable and accessible asset for small-scale producers in Africa, but the effectiveness of vaccination has been limited and rural producers can have their flocks wiped out overnight due to preventable diseases.

PREVENT was launched in April 2021 as an initiative to establish an innovative and pragmatic veterinary health approach in Africa through medium-size hatchery vaccination. PREVENT comprises various workstreams and operations that are connecting the key pieces to achieve this endgame, and in this blog, we explore some of our achievements so far.

  • Hatchery vaccination: The initiative aims to equip 36 mid-size African hatcheries with the necessary equipment and expertise (vaccination techniques, maintenance, hatchery biosecurity practice, quality assurance, and vaccination monitoring) so that the hatcheries will be able to provide customers with large numbers of chicks vaccinated against the major infectious poultry diseases. Farmers and poultry producers buying these vaccinated chicks will have better chances at ensuring flock health, reducing risk of bird losses, securing income, and overall, running more successful businesses. PREVENT has launched activities in 8 countries (Tanzania, Nigeria, Ethiopia, South Africa, Rwanda, Ghana, Burkina Faso, Zimbabwe) and onboarded 24 hatcheries so far. This has allowed the initiative to administer 109 million doses of vaccines to 37 million day-old chicks (an average of 3 vaccine doses per chick). Diseases against which the chicks are vaccinated include Infectious bursal disease, Newcastle disease, Infectious bronchitis, and Marek’s disease.
  • Training and market development: Vaccination alone is not enough, and the lack of technical support and information about circulating infectious diseases is also a major constraint. To date, PREVENT has trained 100 Field Technicians in Tanzania, Nigeria, Ivory Coast, and Ethiopia to provide advice and technical support to small-scale poultry keepers. In serving as the link between the hatcheries and the poultry farmers, the field technicians will also foster demand for, and create markets for vaccinated day-old chicks. Since activities started in September 2022, these field technicians have visited 1,800 farms and held over 100 meetings with farmers.
  • Gender inclusion: The PREVENT initiative seeks to bring a pragmatic level of understanding of gender dynamics within the poultry sector with the goal of positively impacting women chicken producers through the hatchery intervention. To serve this purpose, a rapid gender landscaping analysis was conducted in 3 countries representing East, West, and Southern Africa (Tanzania, Nigeria and Zimbabwe).
  • Epidemiological studies: This is an integrated component of the initiative that aims to explore and describe the epidemiology of poultry diseases at the level of small-scale poultry producers. To date, activity has started in Tanzania, Nigeria and Cote d’Ivoire where 52 samples have been collected.

Introducing changes upstream, at the hatchery level, echoes the positive impact all the way down to the farmer level, and contributes to creating a sound and sustainable system that will lead to an improvement in poultry productivity and efficiency in the targeted African countries.

April 2023 marks the second anniversary of this 4-year initiative. Much has been achieved so far, and much is yet to come.

The PREVENT initiative (PRomoting and Enabling Vaccination Efficiently, Now and Tomorrow) is a partnership between Ceva Santé Animale (a global veterinary health company) and GALVmed, with the support of the Bill & Melinda Gates Foundation.

This blog was written by Patricia Valdeón Noya as part of the campaign “Celebrating 2 years of PREVENT”

Tackling small livestock diseases

Posted on by team galvmed

Almost every small-scale farming family in low- and middle-income countries owns small livestock – whether chickens, ducks, rabbits, sheep, goats or pigs. While small livestock provide nutrient-rich food, they are also considered a form of a savings account and often referred to as “ATMs” because they are a convenient source of cash.

Small livestock are also a pathway out of poverty and source of economic and gender empowerment for women and young people, especially in rural areas.

And yet for millions of small-scale producers, these very important assets are threatened by diseases. A chicken business can be decimated in a blink of an eye by Newcastle Disease (ND) which can kill up to 90% of the poultry. Similarly, Contagious Caprine pleuropneumonia (CCPP) is one of the most severe diseases of goats, and morbidity rate may reach 100% and the mortality rate can be as high as 80%. Peste des petits ruminants (PPR) can cause heavy losses, especially in naïve herds (up to 80%), and African Swine Fever, for which there is no vaccine, has a mortality rate which can be as high as 100%.

These are some of the small livestock diseases that GALVmed and partners are currently tackling. For some of these diseases, there already exist control tools such as a vaccine; for others, not yet. But even for those with vaccines, there are still challenges that impede their wide usage by small-scale producers. Together with our partners, we are continuously researching appropriate technologies to increase their uptake. For example, GALVmed has been working with partners to explore co-administration of the ND-Fowlpox vaccines through a non-invasive, needle free route, using feather follicles for the Fowlpox (FP) and the Newcastle disease vaccine via eye. This research has demonstrated to be safe and to elicit immunity in two field studies, one in Tanzania the other in Nepal. These findings are important to appropriately trained small-scale backyard poultry farmers as well as to paraprofessionals and community health workers helping to increase vaccine uptake and the control of both FP and ND in low- to middle-income countries.

GALVmed is also working with a commercial partner to develop a Small Ruminant Systemic Multivalent Vaccine addressing several major small ruminant diseases (CCPP, SGP, PPR), in a single combination vaccine. The multi-valent approach has the advantage to maximise disease coverage through distribution networks operating effective cold chains.

GALVmed has also previously worked with MCI Sante Animale in Morocco to develop a multivalent vaccine for Peste des petits ruminants (PPR)  and Sheep and Goat Pox (SGP) in sheep and goats. The two diseases affect many of the same animals in the same regions, and are not, in fact, easy to distinguish. Many farmers vaccinate against the more frequently occurring SGP, but not against the less common, but more deadly, PPR.

It is clear that multi-valent vaccines offer pragmatic and cost-effective disease control tools for the small-scale livestock keeper.

Alongside our partners, GALVmed will continue to explore various technologies to address diseases that threaten small livestock, to improve their health, increase their productivity and reduce their mortality, so that small-scale producers can benefit from their small livestock investments.

 This blog was written by Beatrice Ouma as part of the campaign “The advantage of small livestock”

Using a Randomised Control Trial to study the impact of Newcastle Disease vaccine on poultry farmer welfare and livelihoods

Posted on by team galvmed

In 2020, Oxford Policy Management (OPM) was contracted by GALVmed to implement an intervention and conduct an associated impact study on the adoption of a Newcastle Disease Vaccine (NDV) by small-scale poultry farmers in rural Tanzania in the districts of Chemba and Mbozi. The objective of the study is to quantify the causal effects that the delivery of NDV has on the “production, productivity, and livelihoods of small-scale producers (SSPs)”. The study involves two main activities:

  1. The design and implementation of an NDV intervention in selected SSP farming areas of Tanzania.
  2. The design and implementation of an experimental study to quantify the causal effects of the NDV intervention.

The impact study was designed as a randomised controlled trial (RCT) where the study sample was randomly split into one treatment group and one control group. The treatment group was offered and will continue to be offered the NDV intervention package. This group will be compared with a control group, who did not and will not receive the intervention package during the study. The control group will receive one round of the intervention after the study’s endline survey.

A baseline study was conducted between September and November 2021 and the endline survey is scheduled for September to November 2023. Further details on the RCT and its findings will be made available upon publication of the results.

Blog written by Lamyaa Al-Riyami

Hatchery vaccination to boost opportunities for poultry producers in Africa

Posted on by team galvmed

Poultry is an important protein source and an asset for small-scale producers in Africa. However, losses due to preventable diseases continue to significantly impact farmers’ livelihoods and financial stability. Low poultry vaccination combined with inadequate information about circulating diseases and how to treat them form a constant barrier to production by small-scale producers (SSPs).

In April 2021 GALVmed and Ceva Santé Animale launched PREVENT, an initiative designed to establish an innovative and pragmatic veterinary health platform in Sub-Saharan Africa through hatchery vaccination. PREVENT will work with medium-size hatcheries in target countries to annually distribute more than 50 million vaccinated-old-chicks to SSPs. These chicks will be effectively protected against the major infectious poultry diseases thereby improving overall flock health and boosting SSPs’ financial prospects.

Apart from vaccination, there are other key elements in preventing and dealing with animal diseases, such as awareness, knowledge, adequate treatment, etc. In this understanding, the project will train and collaborate with a team of field technicians to assist and provide husbandry advice to poultry SSPs leading to best flock management practices.

PREVENT is an initiative not only focused on the clear benefits of poultry vaccination, but also set to be gender intentional. Intensification in poultry farming typically leads to erosion of the participation of women in management activities. This project will make deliberate efforts to minimise this trend in partner poultry SSPs households.

Lastly, there is a need of building knowledge on diseases that affect small-scale poultry production in scoped countries. To meet this need, an elaborate epidemiological study will be undertaken where samples will be collected at SSPs’ level for further analysis. It is believed that this knowledge will not only be valuable for the project but also inform future interventions.

In a nutshell, by implementing vaccination at the level of the hatcheries, there will be an impact all the way across the value chain that will ultimately improve the sustainability of poultry production system across the target Africa countries (Nigeria, Ivory Coast, Ghana, Tanzania, Ethiopia, Rwanda, and Mozambique). Healthy poultry equals more opportunities to small-scale producers, who will minimise their losses and develop their business to get a more financially secure future.

The PREVENT project was officially launched on April 7, 2021. PREVENT (PRomoting and Enabling Vaccination Efficiently, Now and Tomorrow) is a 4-year initiative in partnership with the animal health company CEVA.

Press release

Written by Patricia Valdeón Noya

All female poultry vaccinators in Ethiopia

Posted on by team galvmed

An all-female vaccinator group is tackling a deadly poultry disease in Ethiopia.

The Newcastle Disease vaccine project in the Tigray region of northern Ethiopia started in January 2017. Its objective was to introduce and implement a Newcastle Disease vaccination and general poultry health and management programme.

In 30 districts in Tigray through female village vaccinators, with the goal to reach 150,000 households, the project aims to empower women whose minimum education qualification is Grade 10 who are categorised as landless women.

(Video by Pius Sawa, WRENmedia consultant, for GALVmed.)